(binding_sample_id, variant_id, umi).
Schema
binding_umi_counts
Contains molecule-level sequencing read counts for candidates and observed sequence variants across samples that underwent antigen selection (binding samples). Before counting reads, alignments are filtered to include only reads that match the candidate sequence with zero errors.
The number of reads observed per Unique Molecular Identifier (UMI) helps determine sequencing saturation for the sample. When each UMI is observed across many reads (for example, dozens or hundreds of times), sequencing is near saturation and additional sequencing depth is unlikely to capture new molecules. Conversely, when read counts per UMI are low, deeper sequencing may capture additional UMIs, allowing more candidate designs and rare sequence variants to be recovered.
Grain: one row per
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